Clevedon Medical Centre is delighted to be able to deliver primary care research to our patient population, giving our patients the opportunity to be involved in important research in order to make a difference to the future of healthcare.


The National Institute for Health Research (NIHR) is the entity that supports the health and care research infrastructure within the NHS. The infrastructure is made up of 15 local Clinical Research Networks (CRNs). CRNs support patients and health professionals to support, deliver and participate in relevant research studies.


Our local CRN is the West of England hosted by the University Hospitals Bristol NHS Foundation Trust. We work closely with the primary care research network within this organisation supporting feasible local and national studies hosted by our network.


Each year we submit our application to be part of the research site initiative scheme. This provides us with funding to host a large number of research projects and the infrastructure to invite and deliver them to our patient population. 

We currently hold the top tier status of research known as sessional.

In order to maintain this status we need to deliver high quality of research opportunities to our patients. We also collaborate with recognised research groups outside of the local CRN in order to bring more opportunities for our patients to become involved in primary care research.

We are a research ready practice, a stipulated requirement to be able to conduct research in primary care.

We may invite you to participate, either opportunistically during an appointment, or by letter. 

Participation is entirely optional and we never release your details to a third party without your prior consent.

Current Studies

antidepressants to prevent relapse in depression (antler)

There is little evidence for the effectiveness of long term maintenance treatment in preventing relapse for depression in primary care. ANTLER is a study designed to estimate the clinical effectiveness of patients continuing long term maintenance antidepressants. The trial is suitable for those who have taken antidepressants for at least 9 months but are now well enough to consider stopping the treatment.

For more information 

 Click Here

Antibiotics for lower Respiratory Tract Infection in Children presenting in Primary Care (ARTIC PC)

Do Antibiotics help children recover from simple chest infections? We do not know, we would like you to help us find out. This study is looking at the effectiveness of Amoxicillin for treating chest infections in children aged 6months to 12 years.

We may invite you to participate during a consultation. Enrolment is entirely optional.


Best Emollient for Eczema (BEE)

BEE is a research study that will improve the treatment of childhood eczema by finding out which emollients (moisturisers) are most acceptable and effective. The study is open to children aged 6 months to 12 years with at least mild eczema.

For more information

Click Here

Renewed Online Study – Cancer: Life Affirming Survivorship support in Primary care (CLASP5)

There is currently an unmet need for tailored support in primary care for cancer survivors to improve their quality of life. This study aims to evaluate an online intervention offering lifestyle and wellbeing support for cancer survivors of breast, colorectal and prostate cancer. Patients who have finished their primary treatment will be invited to participate by a letter of invitation.

For More information

 Click Here

DECIDE: Dapagliflozin pragmatic study

This study is looking at patients with Type 2 diabetes, uncontrolled on maximum tolerated first line therapy (metformin) and comparing the comparative effectiveness between the addition of dapagliflozin (a recognised established oral treatment for diabetes) and usual standard care

Eligible patients may be invited to participate by letter or during their diabetes review

StartRight: Getting the right classification and treatment from diagnosis of diabetes

This study aims to achieve a more accurate early classification of diabetes and identification of which patients will rapidly require insulin treatment. This study is open to patients aged 18-50 diagnosed with diabetes in the last 12 months.

For more information

Click Here

TriMaster: A research study to help improve treatment of Type 2 diabetes, by learning how individuals respond to different blood sugar-lowering drug.

This study is looking at three standard diabetes treatments which can be added when one (metformin) or two (metformin + gliclazide) existing medicines stop maintaining good blood sugar levels (HbA1c >58). It will compare how patients with different blood sugar levels, weight and kidney function respond and which treatments patient prefers.

For more information

Click Here

TReating Urinary symptoms in Men in Primary Healthcare using non-pharmacological and non-surgical interventions.

Half of men over 40 years old experience at least one urinary symptom, which can have a significant effect on their daily lives. This study will test whether a personal booklet given by a Nurse providing advice on men's urinary symptoms improves their symptoms compared to usual care from their GP.

Men who are likely to be eligible for this trial will be sent a letter of invitation 
Join Dementia Research is a service for people to register their interest in participating in dementia research. Anyone over the age of 18, with or without dementia, can register as a volunteer. Please for more details, or you can contact one of the supporting charities: Alzheimer’s society (0300 222 1122) or Alzhemimer’s research UK (0300 111 5111) for more details
Synexus Research: We are collaborating with Synexus to deliver more primary care research opportunities to our patients. Synexus is a company dedicated to conducting clinical studies, and has been investigating the effectiveness of new study drugs and treatments for more than 20 years. You may receive an invitation by letter from the practice to participate in one or more of their research studies if we feel you might be eligible. This is entirely voluntary and will not effect your everyday clinical care from the practice. Please contact Synexus directly if you are interested in participation. Please click here to see their website for more information and studies they are currently undertaking. 

Previous Studies



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