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Anti-Depressant Withdrawal Study
Investigating the neural mechanisms of anti-depressant withdrawal
Investigating brain changes during anti-depressant withdrawal and links with mood, depressive symptoms and relapse.
As part of this study, participants will complete cognitive tasks whilst their brain activity is measured with EEG, they will also complete mental health questionnaires and short surveys.

If you are aware of a patient who is interested in withdrawing from their anti-depressants, please task Natanya Alder or the Research team who can send them a study poster to discuss with their GP at their next appointment.
Who are we looking for?
People currently taking antidepressants (e.g., sertraline or citalopram) who are thinking of stopping their medication.

What’s involved?
You would be asked to complete computer tasks whilst your brain activity is measured with EEG and answer questions about your mental health.
We would also ask you to fill in short surveys about your mood and withdrawal symptoms, a few times a day for a week, via a smartphone app.
You would be asked to do this before you stop taking your antidepressant and again, while you are reducing your dose. Finally we would ask you to fill in some more short surveys and attend a short online session, 6 months after the first meeting.
Benefits of taking part
You will be increasing our knowledge of antidepressant withdrawal. You will be reimbursed for taking part in the study.
Interested in taking part?
You should discuss plans to stop taking your medication with your GP, if you haven’t already. To learn more about the study, please contact Seline Uran (seline.uran@nhs.net, 07354 789341)